Some New Aspects of Statistical Inference for Multistage Dose-Response Models with Applications

Bimal K. Sinha, Leonid Kopylev, John Fox

Abstract


Applications of the results to dose-response multistage models serve as illustrations. The paper considers various scenarios, and is expected to be of interest to practitioners of risk analysis.


Keywords


Benchmark dose, BMDL, Confidence limits, Dose-response models, Likelihood ratio tests, Maximum likelihood estimates, Multistage Weibull model, Parameters on the boundaries, Profile likelihood

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DOI: http://dx.doi.org/10.18187/pjsor.v8i3.519

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Title

Some New Aspects of Statistical Inference for Multistage Dose-Response Models with Applications

Keywords

Benchmark dose, BMDL, Confidence limits, Dose-response models, Likelihood ratio tests, Maximum likelihood estimates, Multistage Weibull model, Parameters on the boundaries, Profile likelihood

Description

Applications of the results to dose-response multistage models serve as illustrations. The paper considers various scenarios, and is expected to be of interest to practitioners of risk analysis.


Date

2012-07-01

Identifier


Source

Pakistan Journal of Statistics and Operation Research; Vol 8. No. 3, 2012



Print ISSN: 1816-2711 | Electronic ISSN: 2220-5810